Cadherin 16 Rabbit mAb

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Cadherin 16 Rabbit mAb

In stock

SKU: A19644 分类: ,
货号 A19644
产品名称Cadherin 16 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
基因名称 CDH16
蛋白名 CDH16
Uniprot/Swissprot ID O75309
Entrez GeneID 1014
克隆号 ARC2212
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse
偶联 Unconjugated
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描述

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

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