Biotinylated Mouse PVRIG Protein C-hFc-Avi Tag | Syd Labs BP003952
(悉得）Syd Labs 货号：BP003952 Biotinylated Mouse PVRIG Protein with the C-hFc-Avi Tag (生物素化小鼠 PVRIG 蛋白 C-hFc-Avi 标签) is expressed from HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Ser35-Asp165.
产品参数
| 货号 | BP003952 |
|---|---|
| 产品名称 | Biotinylated Mouse PVRIG Protein C-hFc-Avi Tag | Syd Labs BP003952 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 物种 | Mouse |
| 来源 | The recombinant Biotinylated Mouse PVRIG Protein, (amino acids Ser35-Asp165) fused with a hFc-Avi tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | A0A1B0GS01 |
| 产品标签 | C-hFc-Avi |
| 生物素化 | yes |
| 确定序列 | Ser35-Asp165 |
| 分子量 | The recombinant Biotinylated Mouse PVRIG protein with the hFc-Avi tag at the C-terminus has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
| 活性 | Immobilized recombinant Mouse Nectin-2 protein with the C-hFc-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Mouse PVRIG protein with the C-hFc tag with the EC50 of 5.04 ug/ml determined by ELISA (QC Test). The affinity constant of 2.22 uM as determined in SPR assay (Biacore T200). |
| Form | Lyophilized |
| 形式 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Biotinylated Mouse PVRIG Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Biotinylated Mouse PVRIG Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 week, 2 to 8°C under sterile conditions after reconstitution. 6 months, -20 to -70°C under sterile conditions after reconstitution. |
| 注意事项 | Conditions of optimal recombinant Biotinylated Mouse PVRIG Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
BP003952: Biotinylated Mouse PVRIG Protein with the C-hFc-Avi Tag (生物素化小鼠 PVRIG 蛋白 C-hFc-Avi 标签)
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.
请记住我们的产品信息: 生物素化小鼠 PVRIG 蛋白 （C-hFc-Avi 标签）BP003952 Syd Labs（Biotinylated Mouse PVRIG Protein with the C-hFc-Avi Tag）.