Biotinylated Human TLR3 Protein C-His Tag (Primary Amine Labeling) | Syd Labs BP004148
(悉得)Syd Labs 货号:BP004148 Biotinylated Human TLR3 Protein with the C-His Tag (生物素化人 TLR3 蛋白 C-His 标签(伯胺标记)) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Glu703.
产品参数
| 货号 | BP004148 |
|---|---|
| 产品名称 | Biotinylated Human TLR3 Protein C-His Tag (Primary Amine Labeling) | Syd Labs BP004148 |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | TLR3; CD283; IIAE2 |
| 物种 | Human |
| 来源 | The recombinant Biotinylated Human TLR3 Protein, (amino acids Ser23-Glu703) fused with a His tag at the C-terminus, was produced in HEK 293 cells. |
| Accession | Q6PCD4 |
| 产品标签 | C-His |
| 生物素化 | yes |
| 确定序列 | Ser23-Glu703 |
| 分子量 | The recombinant Biotinylated Human TLR3 protein with the His tag at the C-terminus has a predicted MW of 78.7 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result. |
| 活性 | Immobilized recombinant Biotinylated Human TLR3 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Anti-TLR3 Antibody protein with the C-hFc tag with the EC50 of 6.6 ng/ml determined by ELISA. |
| Form | Liquid |
| 形式 | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| 制剂 | It is recommended to reconstitute the lyophilized recombinant Biotinylated Human TLR3 Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening. |
| 纯度 | >95% by SEC-HPLC and SDS-PAGE under reducing conditions. |
| 内毒素 | Less than 1 EU per ug of protein as determined by LAL method. |
| 运输 | The recombinant Biotinylated Human TLR3 Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| 稳定性与储存 | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| 注意事项 | Conditions of optimal recombinant Biotinylated Human TLR3 Protein performance should be determined experimentally by the investigator. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品,不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题,欢迎随时联系Syd Labs国内市场推广合作伙伴:武汉多找找科技有限公司,企业微信:duozhaozhao2024 联系电话:18162581039(龙经理) |
文献
BP004148: Biotinylated Human TLR3 Protein with the C-His Tag (Primary Amine Labeling) (生物素化人 TLR3 蛋白 C-His 标签(伯胺标记))
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
请记住我们的产品信息: 生物素化人 TLR3 蛋白 (C-His 标签(伯胺标记))BP004148 Syd Labs(Biotinylated Human TLR3 Protein with the C-His Tag (Primary Amine Labeling) ).

