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货号 | A19702 |
---|---|
产品名称 | Bim Rabbit mAb |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | BAM; BIM; BOD |
基因名称 | BCL2L11 |
蛋白名 | BCL2L11 |
Uniprot/Swissprot ID | O43521 |
Entrez GeneID | 10018 |
克隆号 | ARC0182 |
克隆性 | Monoclonal |
来源 | Rabbit |
反应性 | Human, Mouse, Rat |
偶联 | Unconjugated |
注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
产品咨询 | 悉得(Syd Labs)在国内只通过代理商销售其产品,不做直销。终端用户咨询价格请联系悉得(Syd Labs)中国代理商。 关于悉得(Syd Labs)产品如果有任何技术或其它问题,欢迎随时联系悉得(Syd Labs)国内市场推广合作伙伴:武汉多找找科技有限公司,企业微信:duozhaozhao2024 联系电话:18162581039(龙经理) |
描述
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.