Bad Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Bad Rabbit mAb

In stock

BBC2; BCL2L8

SKU: A19595 分类: ,
货号 A19595
产品名称Bad Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 BBC2; BCL2L8
基因名称 BAD
蛋白名 BAD
Uniprot/Swissprot ID Q92934
Entrez GeneID 572
克隆号 ARC0074
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

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