Alpha-Fetoprotein (AFP) Mouse mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Alpha-Fetoprotein (AFP) Mouse mAb

In stock

AFPD; FETA; HPAFP

SKU: A11865 分类: ,
货号 A11865
产品名称Alpha-Fetoprotein (AFP) Mouse mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 AFPD; FETA; HPAFP
基因名称 AFP
蛋白名 AFP
Uniprot/Swissprot ID P02771
Entrez GeneID 174
克隆号 AMC0029
克隆性 Monoclonal
来源 Mouse
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

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