文献

Background Information:

A selective and orally bioavailable inhibitor of FLT3 currently in clinical trial.

Reference:

1. P.P. Zarrinkar, et al., AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML), Blood, (2009) Vol. 114, No. 14, pp. 2984-2992.

APIM050071: AC220 (QUIZARTINIB)

CAS No.: 950769-58-1.
Molecular Formula: C29H32N6O4S ? 0.3HCl.
Molecular Weight: 571.6.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.