ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)

ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)

ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)

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(悉得)Syd Labs ABflo® 647 Rabbit anti-Human CD45 mAb (Catalog Number: A22495) encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.

SKU: A22495 分类: ,

产品参数

货号 A22495
产品名称ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
基因名称 PTPRC
蛋白名 PTPRC
Uniprot/Swissprot ID P08575-8
Entrez GeneID 5788
克隆性 Monoclonal
来源 Rabbit
反应性 Human
偶联 ABflo® 647. Ex:656nm. Em:670nm.
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文献

A22495: ABflo® 647 Rabbit anti-Human CD45 mAb

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

Immunogen Information about ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 26-577 of human CD45 (P08575).
Sequence:QSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQTPSAGTDTQTFSGSAANAKLNPTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSK
Gene ID:5788
Swiss prot:P08575
Synonyms:LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Calculated MW:138kDa
Observed MW:Refer to figures

Please remember our product information: ABflo® 647 Rabbit anti-Human CD45 mAb (Catalog Number: A22495) (悉得)Syd Labs