ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb (A22630)
(悉得）Syd Labs ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb (Catalog Number: A22630) encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes.
产品参数
| 货号 | A22630 |
|---|---|
| 产品名称 | ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb (A22630) |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | CLA; CD162; PSGL1; PSGL-1 |
| 基因名称 | SELPLG |
| 蛋白名 | SELPLG |
| Uniprot/Swissprot ID | Q14242 |
| Entrez GeneID | 6404 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human |
| 偶联 | ABflo® 488. Ex:491nm. Em:516nm. |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
文献
A22630: ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Immunogen Information about ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb (A22630)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 42-295 of human CD162/PSGL-1 (NP_002997.2).
Sequence：QATEYEYLDYDFLPETEPPEMLRNSTDTTPLTGPGTPESTTVEPAARRSTGLDAGGAVTELTTELANMGNLSTDSAAMEIQTTQPAATEAQTTQPVPTEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQTTPPAATEAQTTQPTGLEAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATEAQTTQPTATEAQTTPLAAMEALSTEPSATEALSMEPTTKRGLFIPFSVSSVTHKG
Gene ID：6404
Swiss prot：Q14242
Synonyms：CLA; CD162; PSGL1; PSGL-1
Calculated MW：43kDa/44kDa
Observed MW：
Please remember our product information: ABflo® 488 Rabbit anti-Human CD162/PSGL-1 mAb (Catalog Number: A22630) (悉得）Syd Labs
