TBP Polyclonal Antibody
Conditions of optimal TBP polyclonal antibody performance should be determined experimentally by the investigator.
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货号 | PA003493-PA1534 |
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产品名称 | TBP Polyclonal Antibody |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | TATA binding factor, TATA sequence-binding protein, TATA-box binding protein, TATA-box factor, TFIID |
同种型 | Rabbit IgG. |
反应性 | Human, Mouse, Rat. |
免疫源 | A synthetic peptide corresponding to a sequence in the middle region of human TBP, identical to the related rat and mouse sequences. |
纯化 | Immunogen affinity purified. |
抗体形式 | Lyophilized. |
稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
注意事项 | Conditions of optimal TBP antibody performance should be determined experimentally by the investigator. |
线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA003493-PA1534: TBP Polyclonal Antibody
Introduction
TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.
Other TBP Antibody:
TBP Polyclonal Antibody