SPARC Polyclonal Antibody

SPARC Polyclonal Antibody

In stock

Conditions of optimal SPARC polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA005171-PA1585 分类: ,
货号 PA005171-PA1585
产品名称SPARC Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 Secreted Protein, Acidic and Rich in Cysteine
同种型 Rabbit IgG.
反应性 Human.
免疫源 A synthetic peptide corresponding to a sequence at the C-terminal of human SPARC.
纯化 Immunogen affinity purified.
抗体形式 Lyophilized.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal SPARC antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA005171-PA1585: SPARC Polyclonal Antibody
Background

SPARC (secreted protein, acidic and rich in cysteine) is a matrix associated protein that elicits changes in cell shape, inhibits cell cycle progression, and influences the synthesis of extracellular matrix (ECM). It is also known as osteonectin (ON) or basement-membrane protein 40 (BM-40). SPARC contains two calcium binding sites; an N-terminal acidic region and a C-terminal extracellular calcium binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC is abundantly expressed in bone, where it promotes osteoblast differentiation and inhibits adipogenesis.
Other SPARC Antibody:
SPARC Polyclonal Antibody

SPARC Protein:
Recombinant Human SPARC Protein

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