Recombinant Human 4-1BB Receptor
Syd Labs Recombinant Human 4-1BB Receptor BP000094-CYT-463, The activity was determined by the inhibition of 4-1BB ligand mediated stimulation of IL-8 production by human PBMC.
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| 货号 | BP000094-CYT-463 |
|---|---|
| 产品名称 | Recombinant Human 4-1BB Receptor |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor T-cell, antigen 4-1BB homolog, T-cell antigen ILA |
| 来源 | E. coli-derived. |
| 形式 | Lyophilized from a concentrated (1 mg/ml) solution in water containing no additives. |
| 纯度 | > 98%, by SDS-PAGE and RP-HPLC. |
| 运输 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| 注意事项 | Conditions of optimal 4-1BBR protein performance should be determined experimentally by the investigator. |
| 线下下单 | 电话: 18162660842微信: duozhaozhao_2017Email: message@sydlabs.comOr 联系我们 |
描述
BP000094-CYT-463: Recombinant Human 4-1BB Receptor
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
BP000094-CYT-463: Recombinant Human 4-1BB Receptor
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 167 amino acids, having a molecular mass of 17718 Dalton and containing the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.
N-terminal sequence analysis: Met-Glu-Arg-Thr-Arg.
The activity was determined by the inhibition of 4-1BB ligand mediated stimulation of IL-8 production by human PBMC. Results: 90% inhibition using 1 ug for both 4-1BB ligand and 4-1BB receptor.
Purity > 98%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 mg/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized 4-1BB Receptor in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other 4-1BBR Protein:
Recombinant Human 4-1BB Receptor, His Tag
Please remember our product information: Recombinant Human 4-1BB Receptor: BP000094-CYT-463 Syd Labs