Phospho-SHC1-Y427 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-SHC1-Y427 Rabbit pAb

In stock

SHC; SHCA

SKU: AP1184 分类: ,
货号 AP1184
产品名称Phospho-SHC1-Y427 Rabbit pAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 SHC; SHCA
基因名称 SHC1
蛋白名 SHC1
Uniprot/Swissprot ID P29353
Entrez GeneID 6464
克隆性 Polyclonal
来源 Rabbit
反应性 Human, Mouse
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

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