Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb

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Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb

In stock

PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1

SKU: AP1340 分类: ,
货号 AP1340
产品名称Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
基因名称 PLCG1
蛋白名 PLCG1
Uniprot/Swissprot ID P19174
Entrez GeneID 5335
克隆号 ARC54936
克隆性 Monoclonal
来源 Rabbit
反应性 Mouse
偶联 Unconjugated
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

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