Phospho-p53-S367 Rabbit pAb
P53; BCC7; LFS1; BMFS5; TRP53
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货号 | AP1170 |
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产品名称 | Phospho-p53-S367 Rabbit pAb |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | P53; BCC7; LFS1; BMFS5; TRP53 |
基因名称 | TP53 |
蛋白名 | TP53 |
Uniprot/Swissprot ID | P04637 |
Entrez GeneID | 7157 |
克隆性 | Polyclonal |
来源 | Rabbit |
反应性 | Human |
注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com |
描述
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).