Phospho-MLKL-S441 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-MLKL-S441 Rabbit pAb

In stock

9130019I15Rik

SKU: AP1174 分类: ,
货号 AP1174
产品名称Phospho-MLKL-S441 Rabbit pAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 9130019I15Rik
基因名称 Mlkl
蛋白名 Mlkl
Uniprot/Swissprot ID Q9D2Y4
Entrez GeneID 74568
克隆性 Polyclonal
来源 Rabbit
反应性 Human, Rat
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene.

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