Phospho-MDM2-S166 Rabbit mAb
HDMX; LSKB; hdm2; ACTFS
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| 货号 | AP1308 |
|---|---|
| 产品名称 | Phospho-MDM2-S166 Rabbit mAb |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | Syd Labs |
| 别称 | HDMX; LSKB; hdm2; ACTFS |
| 基因名称 | MDM2 |
| 蛋白名 | MDM2 |
| Uniprot/Swissprot ID | Q00987 |
| Entrez GeneID | 4193 |
| 克隆号 | ARC2909 |
| 克隆性 | Monoclonal |
| 来源 | Rabbit |
| 反应性 | Human, Mouse, Rat |
| 偶联 | Unconjugated |
| 注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| 产品咨询 | Syd Labs在国内只通过代理商销售其产品，不做直销。终端用户咨询价格请联系Syd Labs中国代理商。 关于Syd Labs产品如果有任何技术或其它问题，欢迎随时联系Syd Labs国内市场推广合作伙伴：武汉多找找科技有限公司，企业微信：duozhaozhao2024 联系电话：18162581039（龙经理） |
描述
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
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