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货号 | AP1188 |
---|---|
产品名称 | Phospho-LAT-Y191 Rabbit pAb |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | LAT1; pp36; IMD52 |
基因名称 | LAT |
蛋白名 | LAT |
Uniprot/Swissprot ID | O43561 |
Entrez GeneID | 27040 |
克隆性 | Polyclonal |
来源 | Rabbit |
反应性 | Human, Mouse |
偶联 | Unconjugated |
注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com |
描述
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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