Phospho-FADD-S194 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-FADD-S194 Rabbit pAb

In stock

GIG3; IMD90; MORT1

SKU: AP1054 分类: ,
货号 AP1054
产品名称Phospho-FADD-S194 Rabbit pAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 GIG3; IMD90; MORT1
基因名称 FADD
蛋白名 FADD
Uniprot/Swissprot ID Q13158
Entrez GeneID 8772
克隆性 Polyclonal
来源 Rabbit
反应性 Human
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
线下下单 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com

描述

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

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