Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Rabbit pAb

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SKU: AP1120 分类: ,
货号 AP1120
产品名称Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Rabbit pAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
基因名称 MAPK1/MAPK3
蛋白名 MAPK1/MAPK3
Uniprot/Swissprot ID P28482/P27361
克隆性 Polyclonal
来源 Rabbit
反应性 Human, Mouse
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

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