Phospho-E-Cadherin-S838/S840 Rabbit pAb
UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
- 产品描述
- 描述
- More Offers
货号 | AP1074 |
---|---|
产品名称 | Phospho-E-Cadherin-S838/S840 Rabbit pAb |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324 |
基因名称 | CDH1 |
蛋白名 | CDH1 |
Uniprot/Swissprot ID | P12830 |
Entrez GeneID | 999 |
克隆性 | Polyclonal |
来源 | Rabbit |
反应性 | Human |
注意事项 | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com |
描述
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.