Phospho-E-Cadherin-S838/S840 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-E-Cadherin-S838/S840 Rabbit pAb

In stock

UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324

SKU: AP1074 分类: ,
货号 AP1074
产品名称Phospho-E-Cadherin-S838/S840 Rabbit pAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
基因名称 CDH1
蛋白名 CDH1
Uniprot/Swissprot ID P12830
Entrez GeneID 999
克隆性 Polyclonal
来源 Rabbit
反应性 Human
注意事项 Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
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描述

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

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