p42 MAPK Polyclonal Antibody
Conditions of optimal p42 MAPK polyclonal antibody performance should be determined experimentally by the investigator.
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货号 | PA000533-R12-3283 |
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产品名称 | p42 MAPK Polyclonal Antibody |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | EC 2.7.11.24, ERK-2, ERK2, ERT1, Extracellular signal- regulated kinase 2, Extracellular signal-regulated kinase 2 |
特异性 | p42 MAPK Antibody detects endogenous levels of p42 MAPK. |
反应性 | Human, Mouse, Rat. |
免疫源 | The antiserum was produced against synthesized peptide derived from human p42 MAPK. |
纯化 | The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. |
抗体形式 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
注意事项 | Conditions of optimal Erk2/p42 MAPK antibody performance should be determined experimentally by the investigator. |
线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA000533-R12-3283: p42 MAPK Polyclonal Antibody
Background
Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme which in humans is encoded by the MAPK1 gene.1 The gene is mapped to 22q11.2.2 And The protein encoded by this gene is a member of the MAP kinase family. The deduced 360-amino acid human ERK2 protein shares 98% identity with rat Erk2.3 The MAP kinase ERK2 is widely involved in eukaryotic signal transduction. Upon activation, it translocates to the nucleus of the stimulated cell, where it phosphorylates nuclear targets.4 Futhermore, the ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex.5 And the MAPK pathway is also involved in responses to NTN1.6 .
Other Erk2/p42 MAPK Antibodys:
p42 MAPK Polyclonal Antibody
ERK2 (MAPK1) Polyclonal Antibody
ERK2 p42 (MAPK) Polyclonal Antibody
ERK2 p42 (MAPK) Polyclonal Antibody(HRP)