NPM Polyclonal Antibody
Conditions of optimal NPM polyclonal antibody performance should be determined experimentally by the investigator.
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| 货号 | PA002595-PA1931 |
|---|---|
| 产品名称 | NPM Polyclonal Antibody |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | Nucleophosmin; Nucleolar phosphoprotein B23, numatrin;Q9BYG9 |
| 同种型 | Rabbit IgG. |
| 反应性 | Human, Rat, Mouse. |
| 免疫源 | A synthetic peptide corresponding to a sequence at the N-terminal of human NPM1, identical to the related rat and mouse sequences. |
| 纯化 | Immunogen affinity purified. |
| 抗体形式 | Lyophilized. |
| 稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| 注意事项 | Conditions of optimal NPM antibody performance should be determined experimentally by the investigator. |
| 线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA002595-PA1931: NPM Polyclonal Antibody
Introduction
NPM1(Nucleophosmin/Nucleoplasmin family, member1), also known as NPM, nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. The NPM1 gene maps to chromosome 5q35. Chan et al. (1989) found that nucleophosmin is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in nucleophosmin protein level. They stated that nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.
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