NOX5 Polyclonal Antibody

NOX5 Polyclonal Antibody

In stock

Conditions of optimal NOX5 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA002591-PA1947 分类: ,
货号 PA002591-PA1947
产品名称NOX5 Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 NADPH oxidase 5,EC 1.6.3
同种型 Rabbit IgG.
反应性 Human.
免疫源 A synthetic peptide corresponding to a sequence at the C-terminal of human NOX5.
纯化 Immunogen affinity purified.
抗体形式 Lyophilized.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal NOX5 antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA002591-PA1947: NOX5 Polyclonal Antibody
Introduction
NOX5(Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. Banfi et al. (2001) found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, Kamiguti et al. (2005) identified NOX5 as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.
Other NOX5 Antibody:
NOX5 Polyclonal Antibody

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