NF-κB2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

NF-κB2 Rabbit mAb

In stock

p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100

SKU: A19605 分类: ,
货号 A19605
产品名称NF-κB2 Rabbit mAb
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
基因名称 NFKB2
蛋白名 NFKB2
Uniprot/Swissprot ID Q00653
Entrez GeneID 4791
克隆号 ARC0084
克隆性 Monoclonal
来源 Rabbit
反应性 Human, Mouse, Rat
偶联 Unconjugated
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描述

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

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