MGMT Polyclonal Antibody
Conditions of optimal MGMT polyclonal antibody performance should be determined experimentally by the investigator.
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货号 | PA002338-PA1408 |
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产品名称 | MGMT Polyclonal Antibody |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | 6-O- methylguanine-DNA methyltransferase, EC 2.1.1.63, MGMT, Methylated-DNA-protein-cysteine methyltransferase |
同种型 | Rabbit IgG. |
特异性 | Human, Mouse, Rat. No cross reactivity with other proteins. |
反应性 | Human, Mouse, Rat. |
免疫源 | A synthetic peptide corresponding to a sequence at the middle region of human MGMT, different from the related mouse sequence by one amino acid. |
纯化 | Immunogen affinity purified. |
抗体形式 | Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. |
稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
注意事项 | Conditions of optimal MGMT antibody performance should be determined experimentally by the investigator. |
线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA002338-PA1408: MGMT Polyclonal Antibody
Introduction
Methylated-DNA-protein-cysteine methytransferase (MGMT) is an enzyme that in humans is encoded by the MGMT gene. O(6)-alkylguanine is the major mutagenic and carcinogenic lesion in DNA induced by simple alkylating mutagens. MGMT gene is mapped to chromosome 10. Rydberg et al. (1990) concluded that the methyltransferase gene spans at least 15 kb. Gardner et al. (1991) refined the localization of the gene to 10q24.33-qter. Methylation of the gene’s promoter plays a significant role in carcinogenesis.
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MGMT Polyclonal Antibody
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