MCM4 Polyclonal Antibody

MCM4 Polyclonal Antibody

In stock

Conditions of optimal MCM4 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA002300-PA1652 分类: ,
货号 PA002300-PA1652
产品名称MCM4 Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 CDC21 homolog, DNA replication licensing factor MCM4, P1-CDC21
同种型 Rabbit IgG.
反应性 Human, Rat, Mouse.
免疫源 A synthetic peptide corresponding to a sequence at the C-terminal of human MCM4,identical to the related rat and mouse sequences.
纯化 Immunogen affinity purified.
抗体形式 Lyophilized.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal MCM4 antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA002300-PA1652: MCM4 Polyclonal Antibody
Introduction
MCM4(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 4),also called CDC21, S. POMBE, HOMOLOG OF, is a protein that in humans is encoded by the MCM4 gene. MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The MCM4 gene is mapped to 8q11.21. The 864-amino acid MCM4 protein has an observed molecular mass of 97 kD by SDS-PAGE, which is similar to its calculated molecular mass of 96.6 kD. Western blot analysis with and without phosphatase treatment suggested that MCM4 is highly phosphorylated in mitotic cells. In the absence of DDK, CDK phosphorylation at the distal part of the Mcm4 NSD becomes crucial.MCM4 encodes a subunit of the MCM2-7 complex (also known as MCM2-MCM7), the replication licensing factor and presumptive replicative helicase.
Other MCM4 Antibody:
MCM4 (Ab-54) Polyclonal Antibody

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