体内实验级重组嵌合人IgG2同型对照抗体
体内实验级重组嵌合人IgG2同型对照抗体（In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody）。体内实验级重组嵌合人IgG2 kappa同型对照抗体和突变体（In vivo grade recombinant chimeric human IgG2 kappa isotype control Antibody and mutants）。与经测试的小鼠样本的特异性结合程度低或无特异性结合。可变区域没有人性化。还提供人性化版本。批量订购价格更低。
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| 货号 | PA007193 |
|---|---|
| 产品名称 | 体内实验级重组嵌合人IgG2同型对照抗体 |
| 英文名 | In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | 重组人IgG2参考抗体，hIgG2同型对照抗体 |
| 概述 | 体内实验级重组嵌合人IgG2 kappa同型对照抗体和突变体（In vivo grade recombinant chimeric human IgG2 kappa isotype control Antibody and mutants）。与经测试的小鼠样本的特异性结合程度低或无特异性结合。可变区域没有人性化。还提供人性化版本。批量订购价格更低。 |
| 克隆号 | 12B9 |
| 同种型 | 人 IgG2, kappa |
| 应用 | 用于ELISA、蛋白质印迹 (WB)、流式细胞术(Flow)、免疫沉淀(IP)、免疫组织化学(石蜡)(IHC (P))、免疫组织化学(Frozen) (IHC (F))和体内动物模型研究的人IgG2 kappa抗体的同型匹配阴性对照。 |
| 免疫源 | N/A |
| 抗体形式 | 0.2 μM过滤溶液，1x PBS |
| 内毒素 | 根据 LAL 方法，≤ 1 EU每 1 mg 蛋白质。提供特级体内实验级重组嵌合人IgG2同型对照抗体（In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody，内毒素≤0.05 EU/mg)。 |
| 纯度 | >95%（在还原条件下通过SDS-PAGE测定） |
| 运输 | 体内实验级重组嵌合人IgG2同型对照抗体（In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody）用冰袋运输。收到后，请立即将其存放在下面建议的温度下。 |
| 稳定性与存储 | 使用手动除霜冰箱并避免重复冻融循环。 如果保存在2 至 8°C，自收到之日起可保存3个月。如果保存在-20 至 -70°C，自收到之日起可保存 12个月。 |
| 注意事项 | 体内实验级重组嵌合人IgG2 kappa同型对照抗体和突变体（In vivo grade recombinant chimeric human IgG2 kappa isotype control Antibody and mutants）。与经测试的小鼠样本的特异性结合程度低或无特异性结合。可变区域没有人性化。还提供人性化版本。批量订购价格更低。 |
| 线下下单 | 武汉多找找科技有限公司 电话: 18162581039 微信: duozhaozhao2024 Email: message@sydlabs.com或联系我们 |
描述
PA007193: 体内实验级重组嵌合人IgG2同型对照抗体（In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody）
背景知识
The recombinant chimeric human IgG2 isotype control（chimeric hIgG2 kappa isotype control antibody）（重组嵌合人IgG2同型对照（嵌合hIgG2 kappa同型对照抗体）） is produced in mammalian cells (CHO cells) like our other recombinant human IgG isotype control and mutant antibodies（重组人IgG同型对照及突变抗体）. The ideal recombinant chimeric human IgG2 isotype control（重组嵌合人IgG2同型对照） has low or no specific binding to any human sample, and murinized or completely murine variable regions in addition to the human IgG2 kappa constant regions. The chimeric human IgG2 kappa isotype control（嵌合人IgG2 kappa同型对照） can be used in the cell-based assay or animal model as the antibody negative control.
Please contact us to ask for a quote for the chimeric hIgG2 isotype control（嵌合hIgG2同型对照） with Avi-, His-, and Flag-tags. A variety of conjugates (such as biotin, dyes, and fluorophores) with the chimeric human IgG2 isotype control（嵌合人IgG2同型对照） are available.
Naturally synthesized and secreted by plasma B cells, the immunoglobulin G (IgG) antibody is the most abundant antibody isotype found in blood and extracellular fluid. There are four IgG subclasses (IgG1, IgG2, IgG3, and IgG4) in humans, of which IgG1 is the most abundantnamed in serum. IgG antibodies are large molecules of about 150 kDa composed of four peptide chains, two identical heavy chains of about 50 kDa and two identical light chains of about 25 kDa. The four peptides are arranged in a Y-shape tetramer by disulfide bonds formed between the two heavy chains and between a heavy chain and a light chain.
The arms of the Y, also called the Fab (fragment, antigen-binding) region containing an identical antigen binding site, is composed of one variable (located at amino terminal end, VH and VL) and one constant domain (CH1 and CL) from each heavy and light chain of the antibody. VH and VL, also called the FV region, is the most important region for binding to antigens. Three variable loops of β-strands, also called the complementarity determining regions (CDRs or idiotypes), on VH and VL respecetively are responsible for binding to the antigen.
The base of the Y, also called the Fc (Fragment, crystallizable) region and composed of two heavy chains with two or three constant domains depending on the class of the antibody, binds to a specific class of Fc receptors and other immune molecules, such as complement proteins, to induce an appropriate immune response for a given antigen. The Fc region bears two highly conserved N-glycosylation sites, one on each heavy chain. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6-linked sialic acid residues.
其它体内实验级重组IgG同型对照抗体和突变体（in vivo grade Recombinant IgG Isotype Control Antibodies and Mutants）:
体内实验级重组人IgG1同型对照抗体和突变体（In vivo Grade Recombinant Human IgG1 Isotype Control Antibody and Mutants）
体内实验级重组人IgG2同型对照抗体（In vivo Grade Recombinant Human IgG2 Isotype Control Antibody）
体内实验级重组人IgG3同型对照抗体（In vivo Grade Recombinant Human IgG3 Isotype Control Antibody）
体内实验级重组人IgG4-S228P同型对照抗体和突变体（In vivo Grade Recombinant Human IgG4-S228P Isotype Control Antibody and Mutants）
体内实验级重组小鼠IgG1同型对照抗体和突变体（In vivo Grade Recombinant Mouse IgG1 Isotype Control Antibody and Mutants）
体内实验级重组小鼠IgG2a同型对照抗体和突变体（In vivo Grade Recombinant Mouse IgG2a Isotype Control Antibody and Mutants）
体内实验级重组小鼠IgG2b同型对照抗体和突变体（In vivo Grade Recombinant Mouse IgG2b Isotype Control Antibody and Mutants）
体内实验级重组小鼠IgG2c同型对照抗体和突变体（In vivo Grade Recombinant Mouse IgG2c Isotype Control Antibody and Mutants）
体内实验级重组小鼠IgG3同型对照抗体（In vivo Grade Recombinant Mouse IgG3 Isotype Control Antibody）
体内实验级重组大鼠IgG1同型对照抗体（In vivo Grade Recombinant Rat IgG1 Isotype Control Antibody）
体内实验级重组大鼠IgG2a同型对照抗体（In vivo Grade Recombinant Rat IgG2a Isotype Control Antibody）
体内实验级重组大鼠IgG2b同型对照抗体（In vivo Grade Recombinant Rat IgG2b Isotype Control Antibody）
体内实验级重组大鼠IgG2c同型对照抗体（In vivo Grade Recombinant Rat IgG2c Isotype Control Antibody）
体内实验级重组仓鼠IgG1同型对照抗体（In vivo Grade Recombinant Hamster IgG1 Isotype Control Antibody）
体内实验级重组仓鼠IgG2同型对照抗体（In vivo Grade Recombinant Hamster IgG2 Isotype Control Antibody）
体内实验级重组IgG Fc蛋白（In vivo Grade Recombinant IgG Fc Proteins）:
体内实验级重组人IgG1-Fc蛋白（hIgG1）（In vivo Grade Recombinant Human IgG1 Fc Protein (hIgG1)）
体内实验级重组人IgG2-Fc蛋白（hIgG2）（In vivo Grade Recombinant Human IgG2 Fc Protein (hIgG2)）
体内实验级重组人IgG4 Fc蛋白（hIgG4）（In vivo Grade Recombinant Human IgG4 Fc Protein (hIgG4)）
体内实验级重组小鼠IgG1-Fc蛋白（mIgG1）（In vivo Grade Recombinant Mouse IgG1 Fc Protein (mIgG1)）
体内实验级重组小鼠IgG2a-Fc蛋白（mIgG2a）（In vivo Grade Recombinant Mouse IgG2a Fc Protein (mIgG2a)）
体内实验级重组小鼠IgG2b-Fc蛋白（mIgG2b）（In vivo Grade Recombinant Mouse IgG2b Fc Protein (mIgG2b)）
体内实验级重组大鼠IgG2a-Fc蛋白（rtIgG2a）（In vivo Grade Recombinant Rat IgG2a Fc Protein (rtIgG2a)）
体内实验级重组大鼠IgG2b-Fc蛋白（rtIgG2b）（In vivo Grade Recombinant Rat IgG2b Fc Protein (rtIgG2b)）
体内实验级重组Llama IgG2b-Fc蛋白（lIgG2b）（In vivo Grade Recombinant Llama IgG2b Fc Protein (lIgG2b)）
体内实验级重组兔IgG Fc蛋白（rIgG）（In vivo Grade Recombinant Rabbit IgG Fc Protein (rIgG)）
Fc-ELISA试剂盒和试剂（Fc ELISA Kits and Reagents）:
人Fc-ELISA试剂盒（Human Fc ELISA Kit）
小鼠Fc-ELISA试剂盒（Mouse Fc ELISA Kit）
人Fc-ELISA试剂盒（Human Fc ELISA Reagent Kit）
小鼠Fc-ELISA试剂盒（Mouse Fc ELISA Reagent Kit）
蛋白质A、树脂、柱和ELISA试剂盒（Protein A, Resin, Columns, and ELISA Kits）：
重组蛋白A（Recombinant Protein A）
蛋白A亲和树脂（Protein A Affinity Resin）
预填充蛋白A柱（Pre-packed Protein A Column）
蛋白A ELISA试剂盒（Protein A ELISA Kit）
请记住我们的产品信息: 体内实验级重组嵌合人IgG2同型对照抗体: PA007193 Syd Labs （In vivo Grade Recombinant Chimeric Human IgG2 Isotype Control Antibody）