CYB5R3 Polyclonal Antibody
Conditions of optimal CYB5R3 polyclonal antibody performance should be determined experimentally by the investigator.
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| 货号 | PA001360-R12-2664 |
|---|---|
| 产品名称 | CYB5R3 Polyclonal Antibody |
| 供货商名称 | Syd Labs, Inc. |
| 品牌名 | 悉得（Syd Labs） |
| 别称 | NADH-cytochrome b5 reductase 3,EC 1.6.2.2; Cytochrome b5 reductase; B5R; Diaphorase-1 |
| 特异性 | CYB5R3 antibody detects endogenous levels of CYB5R3. |
| 反应性 | Human, Mouse, Rat. |
| 免疫源 | The antiserum was produced against synthesized peptide derived from human CYB5R3. |
| 纯化 | The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. |
| 抗体形式 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| 注意事项 | Conditions of optimal CYB5R3 antibody performance should be determined experimentally by the investigator. |
| 线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA001360-R12-2664: CYB5R3 Polyclonal Antibody
Introduction
NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. Two forms of NADH-cytochrome b5 reductase are known, a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The former exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains. The soluble form has only the catalytic domain. This gene encodes both forms of the enzyme which arise from tissue-specific alternative transcripts that differ in the first exon. Mutations in this gene cause methemoglobinemias.
Other CYB5R3 Antibody:
CYB5R3 Polyclonal Antibody
