CKI-A (Ab-321) Polyclonal Antibody

CKI-A (Ab-321) Polyclonal Antibody

In stock

Conditions of optimal CKI-A (ab-321) polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA001201-B1194 分类: ,
货号 PA001201-B1194
产品名称CKI-A (Ab-321) Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 CK1-alpha, CKI-alpha, CSNK1A1, Casein kinase I, alpha isoform, EC 2.7.11.1, KC1A, kinase CK1-alpha
特异性 Casein Kinase 1 α (Ab-321) antibody detects endogenous levels of total Casein Kinase 1 α protein.
反应性 Human, Mouse, Rat.
免疫源 The antiserum was produced against synthesized non-phosphopeptide derived from human Casein Kinase 1 α around the phosphorylation site of threonine 321 (A-Q-TP-P-T).
纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
抗体形式 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal CK1α antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA001201-B1194: CK1α (Ab-321) Polyclonal Antibody
Introduction
Caseine Kinase 1 alpha belongs is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. The CK1 isoforms -alpha, beta, gamma, delta, epsilon and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Possibly CSNK1A1 can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. CSNK1A1 also interacts with the Axin complex.
Other CK1 alpha Antibodys:
CKI-α Polyclonal Antibody
CKI-α Polyclonal Antibody
CSNK1A1 Monoclonal Antibody

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