CD4 Rabbit mAb (A19018)

CD4 Rabbit mAb (A19018)

CD4 Rabbit mAb (A19018)

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(悉得)Syd Labs CD4 Rabbit mAb (A19018) encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules.

SKU: A19018 分类: ,
货号 A19018
产品名称CD4 Rabbit mAb (A19018)
供货商名称 Syd Labs, Inc.
品牌名 Syd Labs
别称 T4; IMD79; Leu-3; OKT4D; CD4mut
基因名称 CD4
蛋白名 CD4
Uniprot/Swissprot ID P01730
Entrez GeneID 920
克隆号 ARC0328
克隆性 Monoclonal
来源 Rabbit
反应性 Human
偶联 Unconjugated
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描述

A19018: CD4 Rabbit mAb

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Immunogen Information about CD4 Rabbit mAb (A19018)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 216-396 of human CD4 (P01730).
Sequence:GEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQP
Gene ID:920
Swiss prot:P01730
Synonyms:T4; IMD79; Leu-3; OKT4D; CD4mut; CD4
Calculated MW:51kDa
Observed MW: 55kDa

Please remember our product information: CD4 Rabbit mAb (Catalog Number: A19018) (悉得)Syd Labs

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