CCBP2 Polyclonal Antibody
Conditions of optimal CCBP2 polyclonal antibody performance should be determined experimentally by the investigator.
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货号 | PA001046-G066 |
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产品名称 | CCBP2 Polyclonal Antibody |
供货商名称 | Syd Labs, Inc. |
品牌名 | 悉得(Syd Labs) |
别称 | Chemokine-binding protein 2;Chemokine-binding protein D6; C-C chemokine receptor D6; Chemokine receptor CCR-9 |
特异性 | CCBP2 antibody detects endogenous levels of total CCBP2 protein. |
反应性 | Human. |
免疫源 | The antiserum was produced against synthesized peptide derived from C-terminal of human CCBP2. |
纯化 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体形式 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
稳定性与存储 | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
注意事项 | Conditions of optimal CCBP2 antibody performance should be determined experimentally by the investigator. |
线下下单 | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
描述
PA001046-G066: CCBP2 Polyclonal Antibody
Introduction
Chemokine-binding protein 2 is a protein that in humans is encoded by the CCBP2 gene. This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
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