CCBP2 Polyclonal Antibody

CCBP2 Polyclonal Antibody

In stock

Conditions of optimal CCBP2 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA001046-G066 分类: ,
货号 PA001046-G066
产品名称CCBP2 Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 Chemokine-binding protein 2;Chemokine-binding protein D6; C-C chemokine receptor D6; Chemokine receptor CCR-9
特异性 CCBP2 antibody detects endogenous levels of total CCBP2 protein.
反应性 Human.
免疫源 The antiserum was produced against synthesized peptide derived from C-terminal of human CCBP2.
纯化 The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
抗体形式 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal CCBP2 antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA001046-G066: CCBP2 Polyclonal Antibody
Introduction
Chemokine-binding protein 2 is a protein that in humans is encoded by the CCBP2 gene. This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
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