BUB1 Polyclonal Antibody

BUB1 Polyclonal Antibody

In stock

Conditions of optimal BUB1 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA000944-R12-2550 分类: ,
货号 PA000944-R12-2550
产品名称BUB1 Polyclonal Antibody
供货商名称 Syd Labs, Inc.
品牌名 悉得(Syd Labs)
别称 BUB1A, BUB1L, EC 2.7.11.1, MBUB1, Mitotic checkpoint BUB1, hBUB1
特异性 BUB1 antibody detects endogenous levels of BUB1.
反应性 Human.
免疫源 The antiserum was produced against synthesized peptide derived from human BUB1.
纯化 The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography.
抗体形式 Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
稳定性与存储 Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
注意事项 Conditions of optimal BUB1 antibody performance should be determined experimentally by the investigator.
线下下单 Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

描述

PA000944-R12-2550: BUB1 Polyclonal Antibody
Introduction
Mitotic checkpoint serine/threonine-protein kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene. Bub1 is a serine/threonine protein kinase first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of Bub1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence.
Other BUB1 Antibody:
BUB1 Polyclonal Antibody

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